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Finally, chart review of WCMC and UIHC datasets revealed over-supplementation (especially of > 50,000 IU weekly doses) in the rare cases of very high 25(OH)D levels.
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Surprisingly, improved 25(OH)D status was observed in patients starting near age 50. Area plots demonstrated a peak of increased 25(OH)D insufficiency / deficiency in adolescent females, although overall worse 25(OH)D status was found in male versus female patients in the WCMC, UIHC, and ARUP datasets. Serum 25(OH)D levels showed seasonal periodicity, with average levels higher in summer than winter and correlating to regional UV index. As expected, average serum 25(OH)D levels were higher in outpatients than inpatients. Average serum 25(OH)D levels were higher in female versus male patients across most ages in the WCMC, UIHC, and ARUP datasets. Results:The majority of tests were ordered on females and outpatients. Chart review was conducted for cases with very high or low serum 25(OH)D levels in the WCMC and UIHC datasets. Methods:Retrospective data queries of 25(OH)D orders and results were conducted using the laboratory information systems at Weill Cornell Medical College / New York Presbyterian Hospital (WCMC), University of Iowa Hospitals and Clinics (UIHC), and ARUP Laboratories (ARUP). Results are also compared to those from a national reference laboratory to determine whether patterns at these two institutions reflect those observed nationally. The present report compares overall utilization and results for 25(OH)D orders at two academic medical centers - one in New York and one in Iowa - in order to characterize the vitamin D status of our inpatient and outpatient populations. Jonathan R Genzen ( ) Jennifer T Gosselin ( ) Thomas C Wilson ( ) Emilian Racila ( )ġ Department of Pathology, University of Utah ARUP Laboratories / ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT, USAĢ Department of Pathology and Laboratory Medicine, Weill Cornell Medical College / New York Presbyterian Hospital, New York, NY, USAģ Department of Psychology, Sacred Heart University, Fairfield, CT, USAĤ Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, USAīackground: Testing for 25-hydroxyvitamin D has increased dramatically in recent years. Result patterns vary by age, gender, season, and patient locationīMC Endocrine Disorders 2013, 13:52 doi:10.1186/1472. Why are doctors reluctant to accept Vit DĪnalysis of vitamin D status at two academic medical centers and a national reference laboratory:.Antibiotics health problems are eerily similar to those due to low Vit D.What might stop you from starting Vit D.Vit D levels dropped by half in 20 years.Health Problem about 10X more likely if low Vit D.If born in wrong season need more Vit D.Receptor gene can limit Vit D actually getting to cells.Health Problems and Vit D (left column).